09:00 - 18:00
Исследования осуществляются ООО "ПраймБиоМед" при грантовой поддержке фонда "Сколково"

Anti-AMACR antibody, clone PBM-G8

Anti-AMACR antibody, clone PBM-G8

Mouse monoclonal anti-AMACR antibody,
clone PBM-G8

Catalog Number 10-310010

Marker binding AMACR

Alternate Names

    •  2-methylacyl-CoA racemase

    •  Alpha-methyl acyl-coenzyme A racemase A

    •  Alpha-methylacyl-CoA racemase (AMACR)

    •  P504S

Type Monoclonal

Clone PBM-G8 (G8)

Host Mouse

Species Reactivity Human

Usage Statement RUO (Research use only)

Suitable for IHC-P, WB

Demasking of antigens According to the datasheet

Isotype IgG2a

Antigen AMACR, peptide

Localisation Cytoplasmic

Positive control Prostate adenocarcinoma

Storage conditions 2-8 °C

Description

AMACR (alpha-methyl acyl-coenzyme A racemase A) is expressed in cells of precancerous intraepithelial neoplasia of the prostate (PIN) with high malignant potential and prostate adenocarcinoma, but is present at low or undetectable levels in normal glandular epithelial cells of the prostate and benign hyperplasia cells. AMACR is the preferred marker for prostate cancer. In addition, AMACR is expressed in normal epithelium and in cells of other adenocarcinoma species.

Packaging

    •  0.1 ml conc. (recommended dilution 1:100)

    •  0.5 ml conc. (recommended dilution 1:100)

    •  1 ml conc. (recommended dilution 1:100)

    •  7 ml diluted, ready to use (RTU)

References

    1. Hameed O, et al. Am J Surg Pathol. 2005 May;29(5):579-87 2. Jiang Z, et al. Hum Pathol. 2003 Aug;34(8):792-6