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Anti-CEA antibody, clone PBM-B2

Anti-CEA antibody, clone PBM-B2

Mouse monoclonal anti-CEA antibody, clone PBM-B2

Catalog Number 10-310013

Marker binding CEA

Alternate Names

    •  Carcinoembryonic antigen (CEA)

    •  CEACAM5

Type Monoclonal

Clone PBM-B2 (B2)

Host Mouse

Species Reactivity Human

Usage Statement RUO (Research use only)

Suitable for

    •  IHC-P

    •  ELISA

Demasking of antigens According to the datasheet

Isotype IgG2a

Antigen CEA, peptide

Localisation Cytoplasmic and membranous

Positive control Prostate adenocarcinoma

Storage conditions 2-8 °C

Description

Carcinoembryonic Antigen (CEA) is found in several adenocarcinomas, such as colon, lung, breast, stomach and pancreas. Malignant mesothelioma is usually negative for CEA. The antibody is a useful tool for the identification of colon carcinomas, and for the distinction of mesothelioma from adenocarcinoma when used with a panel of antibodies (e.g. with Cytokeratin, Calretinin, etc.) 

Packaging

    •  0.1 ml conc. (recommended dilution 1:100)

    •  0.5 ml conc. (recommended dilution 1:100)

    •  1 ml conc. (recommended dilution 1:100)

    •  7 ml diluted, ready to use (RTU)

References

    1. Muraro R, et al. Cancer Res. 1985 Nov;45(11 Pt 2):5769-80

    2. Shi ZR, et al. J Histochem Cytochem. 1994 Sep;42(9):1215-9

    3. Sheibani K, et al. Hum Pathol. 1992 Feb;23(2):107-16