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Mouse monoclonal anti-Cytokeratin 7 antibody,
clone PBM-12F1

Catalog Number 10-310048

Marker binding Cytokeratin 7

Alternate Names

    •  Cytokeratin 7

    •  Keratin 7

    •  KRT7 

    •  CK7

    •  K2C7

    •  K7

    •  SCL

Type Monoclonal

Clone PBM-12F1 (12F1)

Host Mouse

Species Reactivity Human

Usage Statement RUO (Research use only)

Suitable for IHC-P

Demasking of antigens According to the datasheet

Isotype IgG1

Antigen Cytokeratin 7, full size recombinant protein

Localisation Cytoplasmic

Positive control Prostate, lung adenocarcinoma, pancreas

Storage conditions 2-8 °C

Description

Cytokeratin 7 is an intermediate filament protein (IFP) of 54 kDa that recognizes the simple epithelium found in most glandular and transitional epithelia; but not that which is found in stratified squamous epithelia. Cytokeratin 7 is a basic cytokeratin, and is expressed in epithelial cells of ovary, lung, and breast, but not of colon or gastrointestinal tract. It is often used in conjunction with cytokeratin 20 in distinguishing ovarian, pulmonary, and breast carcinomas (CK7+) from colon carcinomas (CK7-).

Packaging

    •  0.1 ml conc. (recommended dilution 1:100)

    •  0.5 ml conc. (recommended dilution 1:100)

    •  1 ml conc. (recommended dilution 1:100)

    •  7 ml diluted, ready to use (RTU)