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Anti-Cytokeratin (Pan) antibody, clone C11

Anti-Cytokeratin (Pan) antibody, clone C11

Mouse monoclonal anti-Cytokeratin (Pan) antibody, clone C11

Catalog Number 10-310015

Marker binding Cytokeratin (Pan)

Alternate Names

    •  Pancytokeratin (Cytokeratin-Pan)

    •  Pankeratin (Keratin-Pan)

    •  CK-Pan

Type Monoclonal

Clone C11

Host Mouse

Species Reactivity Human

Usage Statement RUO (Research use only)

Suitable for IHC-P, WB

Demasking of antigens According to the datasheet

Isotype IgG1

Antigen Cytokeratin (Pan), native cytokeratins: 4, 5, 6, 8, 10, 13 and 18

Localisation Cytoplasmic

Positive control Epithelial tissue

Storage conditions 2-8 °C

Description

Antibodies binds to cytokeratins (4, 5, 6, 8, 10, 13, and 18) of simple epithelium and tumor derivatives and are expressed in stratified squamous epithelium. Cytokeratins are known markers of tissue differentiation and are used to determine the malignancy of tumors. Positive staining results contribute to the classification of normal and neoplastic tissues of epithelial origin. C11 antibodies can be used as part of antibody panels for the differential diagnosis of tumors of various etiologies: mammary gland (CK7, CEA), GCDFP-15, TTF-1), lung or liver (CK7, CEA), GCDFP-15, TTF -1); kidney (CEA), TTF-1), seminomes (CAM5.2, CK C11, PLAP, EMA, CD30); as well as for the identification of embryonic germ cells (TTF-1, CK7).

Packaging

    •  0.1 ml conc. (recommended dilution 1:100)

    •  0.5 ml conc. (recommended dilution 1:100)

    •  1 ml conc. (recommended dilution 1:100)

    •  7 ml diluted, ready to use (RTU)

References

    1. Moll R, et al. Cell. 1982 Nov;31(1):11-024

    2. Kvarik J, et al. Int J Cancer Suppl. 1988; 3:50-05